Personalized Medicine and Pharmacogenomics: Clinical Implications for Optimized Drug Therapy
Keywords:
Personalized Medicine, Pharmacogenomics, Precision Therapy, Drug Response, Clinical PharmacologyAbstract
Personalized medicine represents a paradigm shift in clinical drug therapy by tailoring treatment strategies according to individual patient characteristics. Pharmacogenomics, the study of genetic variations influencing drug response, has emerged as a cornerstone of personalized therapeutics. Conventional drug therapy often follows a “one-size-fits-all” approach, leading to variable efficacy and adverse drug reactions. This review explores the clinical applications of pharmacogenomics, its role in optimizing drug efficacy and safety, current clinical implementation challenges, and future directions for precision medicine.
DOI: 10.8612/36.3.2021.2