Advances in Drug Development: A Comprehensive Review of Novel Therapeutic Approaches

Abstract

The pharmaceutical industry has witnessed a revolutionary transformation in drug development, integrating advanced technologies such as artificial intelligence (AI), nanotechnology, personalized medicine, and biopharmaceuticals to enhance therapeutic efficacy. These novel approaches improve drug discovery, target specificity, bioavailability, and patient-centered treatment strategies.

This paper provides a comprehensive review of emerging methodologies reshaping drug development, including high-throughput screening, predictive modeling, AI-driven drug repurposing, pharmacogenomics, and nanoparticle-based drug delivery systems. In addition, it explores challenges associated with drug resistance, ethical considerations in pharmaceutical research, and regulatory frameworks governing modern therapeutics.

Through an in-depth examination of research advancements, this paper highlights the significance of precision medicine, AI-driven innovations, and biopharmaceutical breakthroughs in ensuring improved patient outcomes. The implications of these advancements on healthcare accessibility and future drug development prospects are also discussed.

DOI: 10.8612/37.4.2022.3